Course Objectives

• This course covers the actions, uses, adverse effects and mode of administration of drugs, especially related to eyes.

Learning Outcomes

• At the end of the course the students will acquire knowledge in the following aspects-

  1. Basic principle of pharmacokinetics & Pharmacodynamics

  2. Commonly used ocular drugs, mechanism, indications, contraindications, drug dosage and adverse effects.

Course Syllabus

Module-1(8 hours)

Pharmacokinetics: Drug absorption, distribution, metabolism and excretion

Module-2 (8 hours): Pharmacodynamics: Drug Handling by the body – effect of drug and the relationship between drug concentration and response, Drug – Receptor interactions

Module-3 (8hrs)

Ocular Pharmacology: Drug Handling by cells and Tissues – Pharmacokinetics, and Pharmacodynamics– specific to ocular – surface and intraocular conditions

Module-4 (6hrs)

Delivery methods of Ocular Medication: Residence in the conjunctival sac, drug vehicles affect drug delivery, advanced ocular delivery systems, Reconstituting the tear film: Tear Substitutes ,

Module-5 (6hrs)

Ocular Drugs and the Autonomic Nervous system: Parasympathetic( anti muscaranic) and Sympathetic

Module-6(6hrs)

Intraocular pressure Drugs, Eicosanoids: prostaglandins, thromboxaes   and leukotrienes, Serotonin

Module: 7 (6hrs)

Neurotransmitter; Glucocorticoids, Immunosuppressive agents, Local Anesthetics, Ocular Toxicity from systemic administration of Drugs supervised setting.

Text Books

• K D TRIPATHI : Essentials of Medical Pharmacology. 4^th,2003
• T S MAUGER & E L CRAIG - MOSBY'S - OCULAR DRUG HANDBOOK

Reference Book:

• Zimmerman: Text Book of Ocular Pharmacology,1999
• Bartlett and Jaanus: Clinical Ocular Pharmacology
• S P RANG , M M DALE, RITTER – Pharmacology, Ed.3 Churchill 1995.

Session Plan

Session 1 & 2

Pharmacokinetics Introduction & Drug absorption

https://www.youtube.com/watch?v=8-Qtd6RhfVA

https://www.slideshare.net/pooranachithraflowry/introduction-to-pharmacokinetics-and-pharmacodynamics-principles

https://www.youtube.com/watch?v=pWW-aq7iSa0

https://www.slideshare.net/animeshgupta583/drug-absorption

Session 3 & 4

Drug distribution

https://www.youtube.com/watch?v=6erefsWCVxg

https://www.slideshare.net/UmasankarKrishnamaraju/drug-distribution-40685564

Session 5 & 6

Drug metabolism

https://www.youtube.com/watch?v=oCPRi5JFMdg

https://www.slideshare.net/swaroophassan/drug-metabolism-40740005

Session 7 & 8

Drug excretion

https://www.youtube.com/watch?v=VZRVt9r4oSM

https://www.slideshare.net/sarita1916/drug-excretion-72976060

Session 9 & 10

Pharmacodynamics: Drug Handling by the body – effect of drug and the relationship between drug concentration and response

https://www.youtube.com/watch?v=VzrvklX5Wmw

https://www.slideshare.net/saurabhwani77/dose-response-relationship

Session 11, 12, 13, 14, 15 & 16

Drug – Receptor interactions

https://www.youtube.com/watch?v=YonbZHGYMt4

https://www.slideshare.net/siddharthadutta8/receptor-pharmacology-types-and-drug-receptor-interactions

Session 25, 26, 27, 28, 29 & 30

Delivery methods of Ocular Medication: Residence in the conjunctival sac, drug vehicles affect drug delivery, advanced ocular delivery systems, Reconstituting the tear film: Tear Substitutes

Session 17, 18, 19, 20, 21, 22, 23 & 24

Ocular Pharmacology: Drug Handling by cells and Tissues – Pharmacokinetics, and Pharmacodynamics– specific to ocular – surface and intraocular conditions

https://www.youtube.com/watch?v=mhXvLfsLgrQ

https://www.youtube.com/watch?v=guspTGxUO_c

https://www.slideshare.net/guest86523812/ocular-pharmacology

https://www.slideshare.net/osaidtaisir7/ocular-pharmacokinetics-81399267

https://www.slideshare.net/DrVishalPawar/ocular-pharmacology-105610058

Session 31, 32, 33, 34, 35 & 36

Ocular Drugs and the Autonomic Nervous system: Parasympathetic( antimuscaranic) and Sympathetic

https://www.youtube.com/watch?v=3a_aLsFvNWs

https://www.youtube.com/watch?v=ADnWvmOlBZk

https://www.youtube.com/watch?v=zDT4f0TKj3k

https://www.youtube.com/watch?v=Usc6UobwGpw

https://www.slideshare.net/drdhriti/ans-pharmacology-and-cholinergics-drdhriti-updated-2011

Session 37, 38, 39, 40, 41 & 42

Intraocular pressure Drugs, Eicosanoids: prostaglandins, thromboxanes   and leukotrienes, Serotonin

https://www.youtube.com/watch?v=2n3J5fCILmk

https://www.youtube.com/watch?v=018PxnH702k

https://www.youtube.com/watch?v=Kdgu6WRJtUE

https://www.slideshare.net/BikashSapkota/antiglaucoma-drugs

https://www.slideshare.net/DipeshTamrakar2/eicosanoids-86482397

https://www.slideshare.net/GeetaJaiswal1/prostaglandin-leukotriene-and-thromboxane

Session 43, 44, 45, 46, 47 & 48

Neurotransmitter; Glucocorticoids, Immunosuppressive agents, Local Anesthetics, Ocular Toxicity from systemic administration of Drugs supervised setting.

Case Studies

Case Studies

Course Objectives

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Learning Outcomes

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Course Syllabus

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Session Plan

Session 1

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Session 2

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Case Studies

Case Studies